Cap and UTP

core raw materials for mRNA synthesis

RhCap001(ammonium salt)

RhCap001 is a new type of cap-like object with proprietary intellectual property rights. This product is used for transcription with a starting sequence of 5'AG3'. Compared to the Cap1 and Cap0 generated by traditional capping methods, the EM1003 cap structure allows mRNA to have higher in vivo activity and translation efficiency.
core raw materials for mRNA synthesis

N1-Me-Pseudo-UTP(sodium salt)

N1-Me-Pseudo-UTP is a modified nucleotide used in various molecular biology applications such as in vitro transcription and siRNA synthesis. It can be added to mRNA through in vitro transcription to reduce the mRNA's immunogenicity and improve its expression efficiency by increasing ribosome binding. Experimental evidence has shown that N1-Me-Pseudo-UTP can further enhance mRNA expression efficiency in cells and mice compared to pseudo-UTP, while reducing mRNA's immunogenicity. This product is a sodium salt solution of N1-Me-Pseudo-UTP with a purity of≥ 98% (HPLC), a concentration of 100mM±5mM, and no contamination of endonucleases, exonucleases, and ribonucleases.
core raw materials for mRNA synthesis

Pseudo UTP(sodium salt)

Pseudouridine triphosphate (pUTP) is a commonly used modified nucleotide in molecular biology. It finds various applications, such as in vitro transcription and siRNA synthesis. Studies have shown that mRNA synthesized using pUTP has improved stability, translation efficiency, and reduced immunogenicity, making it widely used in the field of disease research. Our product is a sodium salt solution of pUTP with a purity of≥ 96% (HPLC) and a concentration of 100mM±5mM. It is free from contamination of endonucleases, exonucleases, and ribonucleases.