N1-Me-Pseudo-UTP(sodium salt)
Description
N1-Me-Pseudo-UTP is a modified nucleotide used in various molecular biology applications such as in vitro transcription and siRNA synthesis. It can be added to mRNA through in vitro transcription to reduce the mRNA's immunogenicity and improve its expression efficiency by increasing ribosome binding. Experimental evidence has shown that N1-Me-Pseudo-UTP can further enhance mRNA expression efficiency in cells and mice compared to pseudo-UTP, while reducing mRNA's immunogenicity. This product is a sodium salt solution of N1-Me-Pseudo-UTP with a purity of≥ 98% (HPLC), a concentration of 100mM±5mM, and no contamination of endonucleases, exonucleases, and ribonucleases.
Product Information
| Product Type | core raw materials for mRNA synthesis |
|---|---|
| Category | nucleotide |
| Art.No | EM2001 |
| Scale | 50 ul-100 ml (Customizable packaging is available) |
| Purity/% | ≥98% |
| Storage buffer | H2O |
| Storage temperature | -20℃ |
| Transportation | Dry ice |
| Molecular weight | 498.17 |
| Molecular formula | C10H17N2O15P3 |
| Concentration/mM | 100~120(customizable) |
Note
The solution form is generally not suitable for long-term storage, please use up as soon as possible
Product manual
N1-Me-Pseudo-UTP(sodium salt)Product manual